Human and animal rights ethical statement

All research involving human participants and animal work must have been approved by the authors' institutional review board or equivalent committee(s) and that board must be named by the authors in the manuscript. For research involving human participants, informed consent must have been obtained (or the reason for lack of consent explained, e.g. the data were analyzed anonymously) and all clinical investigations must have been conducted according to the principles expressed in the Declaration of Helsinki. For a research involving in animals experiments, at the beginning of the Methods section of your manuscript (with the subheading Ethics Statement) enter: "Investigation has been conducted in accordance with the ethical standards and according to the Declaration of Helsinki and according to national and international guidelines and has been approved by the [authors' institutional review board]."