Table of Contents

• The role of adipose tissue aging in organismal aging

  Al Maskari Raya, Nomier Yousra

  Aging, a complex process marked by the progressive decline in cellular and systemic functions, increases vulnerability to metabolic and age-associated disorders. Adipose tissue, being the largest energy reservoir in the body, plays a crucial role in regulating metabolism and maintaining energy balance. Adipose tissue exhibit early onset of age-associated dysfunctions, which ultimately contribute t...

  REVIEW | Published: 23 Feb 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Online First

  Pages: 28-37   PDF(2470KB)   Views：64Downloads：2

• Molecular bases of adipose tissue aging

  Aakeel Ahmad, Manlio Fusciello

  Aging impacts each and every living organism. In higher organisms, it is an asynchronous process with its onset and pace varying among tissue types as well as among different cell types within a tissue. Adipose tissue is the largest energy depot in the body and is an endocrine organ responsible for metabolic homeostasis. Adipose tissue aging is marked by fat redistribution, with increased visceral...

  REVIEW | Published: 14 Feb 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Online First

  Pages: 19-27   PDF(1740KB)   Views：94Downloads：5

• The role of cardiovascular aging in heart failure

  Denise Greco, Kofi Oti Boakye-Yiadom

  Cardiovascular aging represents a critical factor contributing to the rising prevalence of heart failure in aging populations, as structural and functional changes occurring in the heart and vasculature during aging result in an increased susceptibility to heart failure. Different aging-related molecular mechanisms contribute to these cardiovascular changes. Among these molecular mechanisms are ep...

  REVIEW | Published: 29 Jan 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Online First

  Pages: 9-18   PDF(1450KB)   Views：95Downloads：1

• Mid-life: a critical window for intervention during aging

  Evandro Lopes de Carvalho

  Mid-life represents a pivotal period marked by profound physiological and metabolic transitions, increasing susceptibility to chronic diseases. This review explores the molecular and systemic underpinnings of mid-life transition by integrating insights from recent studies that elucidate aging-associated changes in the plasma proteome, immune system, adipose tissue remodeling, and cellular senescen...

  REVIEW | Published: 14 Jan 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Online First

  Pages: 1-8   PDF(1340KB)   Views：158Downloads：5