Table of Contents

• Healing through movement: narrative review on exercise and neurological disorders

  Syed Muhammad Essa, Amanullah Kakar ... Karolina Riddle

  Exercise has great potential for enhancing brain health and preventing or treating neurological conditions. Three molecular pathways have been identified: neuroprotection, neurotrophic factor increase, and neurotransmitter modulation. We reviewed PubMed, Scopus, and Google Scholar according to PRISMA criteria. The inclusion criteria included studies with peer review providing molecular insights i...

  REVIEW | Published: 20 Dec 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Volume 2

  Pages: 73-84   PDF(1250KB)   Views：135Downloads：1

• The influence of the gut-brain axis on neurological and psychiatric well-being

  Muhammad Sufyan, Mohammad Amjad Kamal

  The biological neurocentric view of brain health is being fundamentally organized by our understanding of the gut-brain axis (GBA). A complex, bidirectional communication network corelating the gastrointestinal tract with the central nervous system. This review represents current evidence on the profound influence of the GBA on neurological and psychiatric well-being, highlighting the gut microbio...

  REVIEW | Published: 21 Oct 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Volume 2

  Pages: 58-72   PDF(2790KB)   Views：78Downloads：1

• Relationship between leptin receptor and TNF-α in obesity and polycystic ovary syndrome

  Omnia Mohamed Attia, Ahmed Attia Ahmed Abdelmoaty

  The pathophysiology of polycystic ovarian syndrome (PCOS), a prevalent endocrine disorder, is intimately associated with obesity, particularly the abdominal phenotype. This accumulation of visceral fat is one of the primary causes of insulin resistance and the resulting metabolic dysregulation. Two key mediators in this process are leptin and TNF-α. The adipokine leptin regulates energy balance an...

  REVIEW | Published: 25 Aug 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Volume 2

  Pages: 48-57   PDF(1040KB)   Views：228Downloads：3

• Aging-related comorbidities, life-style interventions and therapeutic strategies in heart failure

  Nam Nhut Phan, Fakhar-un-Nisa Yunus

  Aging is a key risk factor for heart failure which significantly contributes to progressive structural and functional deteriorations in the heart, such as increased incidence of left ventricular hypertrophy, decline in left ventricle diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac amyloidosis, all contributing to compromised cardiac performance and le...

  REVIEW | Published: 30 Mar 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Volume 2

  Pages: 38-47   PDF(1670KB)   Views：778Downloads：4

• The role of adipose tissue aging in organismal aging

  Al Maskari Raya, Nomier Yousra

  Aging, a complex process marked by the progressive decline in cellular and systemic functions, increases vulnerability to metabolic and age-associated disorders. Adipose tissue, being the largest energy reservoir in the body, plays a crucial role in regulating metabolism and maintaining energy balance. Adipose tissue exhibit early onset of age-associated dysfunctions, which ultimately contribute t...

  REVIEW | Published: 23 Feb 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Volume 2

  Pages: 28-37   PDF(2470KB)   Views：1125Downloads：7

• RETRACTED: Molecular bases of adipose tissue aging

  Aakeel Ahmad, Manlio Fusciello

  No abstract....

  RETRACTED ARTICLE | Published: 07 Apr 2025

  Asia-Pacific Journal of Surgical & Experimental Pathology, Articles, Volume 2

  Pages: 19-27   PDF(1740KB)   Views：844Downloads：31